The Hidden Fat Underneath Your Belly is NOT Always Bad (Visceral Fat)

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Is there a purpose for VISCERAL FAT? If so, what is that purpose? Well, if it's inside our body, it's there for a reason. So let's take a look at the role visceral fat plays in our health. Let's dive in and I'll see you in the COMMENTS!!

Per a study in Digestive Diseases entitled, “The Role of Visceral Fat” stated that visceral fat “recognizes danger”

Recognition of Danger by Visceral Fat

The release of free fatty acids by adipocytes following LPS stimulation, and hence responsiveness of fat cells to bacterial components, is an effect detected over 30 years ago

In the next step, the expression of the pattern recognition receptors Toll-like receptors (TLR) 2 and 4 was detected on adipocytes generated from the 3T3L1 cell line

*Toll-like receptors (TLRs) are a class of proteins that play a key role in the innate immune system. They are single-pass membrane-spanning receptors usually expressed on sentinel cells such as macrophages and dendritic cells, that recognize structurally conserved molecules derived from microbes.*

Basically TLRs they have critical role in the early innate immune response to invading pathogens by sensing microorganism and are involved in sensing endogenous danger signals - they detect and recognize pathogen-associated molecular patterns derived from microbes*

Adipocytes express a broad set of TLRs and that specific stimulation induces secretion of immune regulatory mediators

In addition, the expression of pattern recognition receptors is not restricted to TLR - preadipocytes express the functional intracellular pattern recognition receptors nucleotide oligomerization domains (NOD) 1 and 2 - expression of NOD1 is regulated by TNF-
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